
"That's the end of your Looney Tunes, Drugs Bunny." ---Chief Wiggum
After Bart wreaks havoc on Springfield Elementary, Marge and Homer agree to put Bart on an experimental, mind-altering medication so that he won't be expelled. Principal Skinner shows that Bart's bad behavior affects other students negatively. He shows Marge and Homer a chart of Bart's classroom. The students around Bart all have poor grades, but the ones farthest away from him have good grades. Principal Skinner notes that Bart clearly suffers from Attention Deficit Disorder (ADD). He tells Marge and Homer that ADD can cause children to become restless and easily distracted. While he is telling the Simpsons this, Homer is messing around with an item from Principal Skinner's desk and is clearly not paying attention. This suggests that Bart is similar to his father and that there may be a link between genes and ADD.
An important dialogue between the psychiatrist and Bart's parents occurs during the episode. When describing the ADD medication, the psychiatrist says, "This pill reduces class-clown-ism 44%, with 60% less sass-mouth." The psychiatrist proceeds to tell Homer and Marge, "The only thing more effective is regular exercise." Homer gasps and shudders. This dialogue pokes fun at the overuse of ADD medications and the ignorance of other potentially effective and safer methods of treating restless children.
After Bart starts taking the medication, called "Focusin," his behavior and school performance improve dramatically. He does not get into trouble, spends time in his room reading quietly, and greatly increases his productivity. However, Focusin does have some negative side effects. Eventually, Bart becomes paranoid and wraps himself in foil because he believes that people are spying on him and trying to read his thoughts. When Marge and Homer bring him back to the psychiatrists, the doctors blame Bart's reaction on a carboxyl group. They plan to switch Bart's medications and start him on some of Focusin's "sister drugs." Bart vehemently protests this switch, quickly gobbles up a handful of Focusin pills, and runs out the door, suggesting that Bart is attached to and dependent on the psychotropic drug.
In the end, after a series of unrealistic events, Bart is taken off the medication, and everything in the Simpson family returns to normal.